Joseph Tedesco, Ph.D.

President, Key Molecular Corp., Toronto, Canada

Phone: 416-876-1500 email: jtedesco@keymolecular.com

 

EDUCATION AND TRAINING

 

Scientific Publications: Listed here

University of Toronto: Ph.D. 1984 (Pharmacology),  M.Sc. 1973;  B.Sc. 1969.

 

Selected Other Courses:

          2001: Certification as Mediator, trained for ADR (Alternative Dispute Resolution) within the Federal Government SR&ED Program; sponsored by Revenue Canada.

 

 

AREAS OF SPECIALIZATION

 

          SR&ED Claims Support & Guidance

          Organic Chemistry- Design Syntheses

          Molecular Pharmacology

          Food Chemistry Projects

          Software Algorithms

          Contract Science/Engineering Projects

 

 

SR&ED WORK As Scientific Consultant:

 

            1991-2022:    Scientific Consultant to Private Sector & Government.

 

1.            SR&ED - for Revenue Canada (CRA):  1993-2003

                Over 11 years,  performed technical reviews or audits, as an Outside Science Expert, of "Scientific Research and Experimental Development" (SR&ED) Tax Claims for Investment Credits made by Canadian Corporations in the following sectors:

       Generic drug companies, large and small

       Contract Research or Manufacturing Companies

        Biotechnology companies;

                These activities involved evaluating over one billion dollars in corporate expenditures.  Work was also done for the SR&ED Appeals Branch in Ottawa.

 

2.            SR&ED - for Private Sector:  Wrote or guided over 40 SR&ED claims on behalf of companies doing  projects in Mechanical Engineering, Agricultural Science, Software and Food Engineering. Dr. Tedesco has also successfully filed over 30 SR&ED claims for Key Molecular Corp. since its founding.

 

  3.            Related Scientific & Forensic Investigations: for the Legal & Insurance Professions. Critiqued the scientific validity of insurance claims by private sector companies & individuals. Tested claims that a service or a product was deficient.

 

AWARDS

                           8 Scholarships and Fellowships.

        Ontario Mental Health Fellowship  1974-1978

         Annual Research Fund Award (1976) of the Clarke Institute of Psychiatry (Toronto):  "For an outstanding research dissertation within the field of Mental Health published during 1975"; senior author was Philip Seeman, with co-authors M. Chau‑Wong and K. Wong and J. Tedesco :  For the world's  first successful demonstration (through binding) of the existence of the dopamine receptor (P.N.A.S.(U.S.A)  72  4376‑4380, 1975.).

 

Milestones as Head of Key Molecular Corp.

 

1988-Current:

      2001-2017:        DESIGN, SYNTHESIS & SALE OF MANY NEW RESEARCH  CHEMICALS.

      1994-2017:        DEVELOPMENT  OF  SOFTWARE  FOR  NOVEL  DRUG-DESIGN SYSTEMS.

      1992 - 1993:      DESIGN  AND  SYNTHESIS  OF  NEW  DRUGS FOR  SCHIZOPHRENIA  AND  PARKINSONISM.

Partnering with Allelix Pharmaceuticals & with colleagues at the University of Toronto.  

          1990 - 1991:      KINETICS  OF  IONIC  RELEASE  FROM  POROUS BIOMATERIALS:   Product Improvement Program for Chinook Corp., a large Canadian company. Built a novel computer-integrated system for analysis of the temporal pattern of ionic release from slow-release particles.

           Developed a novel enzymatic assay for choline chloride.

       1988 ‑ 1990:        CHOLESTEROL REMOVAL R&D PROJECT:

          Development  of  a  commercial  technology for  the  selective  extraction  of  cholesterol from  egg‑yolk  and  dairy  foods.

 

 

ACADEMIC  POSITIONS

 

              Research Associate, University of Toronto, Department of Chemistry

                1985 - 1987

                Function:  Head of Biochemistry division in the Chemical Sensors Group at U of T Mississauga Campus.

Duties and Accomplishments:

1.      Scientific director of a staff of  biochemical technicians, within a team of 6 scientists. This project was financed by a $3 million contract between Allied-Signal Corp. and the University of Toronto.

2.      Basic research on biological receptors for the applied development of analytical sensing devices. Set up new laboratory for this work.

3.      Scientific Communications: presented findings in seminars and meetings.

 

              Visiting Professor - Chemistry Department, University of Toronto

                1993-1995

          worked on new drugs for schizophrenia and parkinsonism,  collaborating in organic chemistry  projects with Prof. Peter Yates.

 

PUBLICATIONS

          Scientific Publications: Listed here